Publications

Discovering Algorithms with Computational Language Processing
Discovering Algorithms with Computational Language Processing
Authors: Theo Bourdais, Abeynaya Gnanasekaran, Houman Owhadi and Tuhin Sahai
Published in: arXiv • July 2025
Gaussian Processes Hypergraphs Machine Learning Computational Science

This paper introduces Computational Hypergraph Discovery (CHD), a novel method for uncovering unknown functional relationships between variables within datasets, and represent them using a hypergraph.

Pruning Deep Neural Networks via a Combination of the Marchenko-Pastur Distribution and Regularization
Pruning Deep Neural Networks via a Combination of the Marchenko-Pastur Distribution and Regularization
Authors: Theo Bourdais and Houman Owhadi
Published in: arXiv • March 2025
Deep Learning Neural Network Pruning Random Matrix Theory Vision Transformers

We use Random Matrix Theory and regularization to prune deep neural networks, achieving state-of-the-art results on ImageNet with Vision Transformers. We also provide theoretical justification for our approach.

Model aggregation: minimizing empirical variance outperforms minimizing empirical error
Model aggregation: minimizing empirical variance outperforms minimizing empirical error
Authors: Theo Bourdais and Houman Owhadi
Published in: ICLR 2025 • September 2024
Model Aggregation Machine Learning Ensemble Methods Variance Minimization

We present a general framework to combine existing models in a robust manner. Our method is flexible, places few assumptions on the models aggregated, and performs well in our experiments.

Codiscovering graphical structure and functional relationships within data: A Gaussian Process framework for connecting the dots
Codiscovering graphical structure and functional relationships within data: A Gaussian Process framework for connecting the dots
Authors: Theo Bourdais, Pau Batlle, Xiyang Yang, Ricardo Baptista, Nicolas Rouquette and Houman Owhadi
Published in: PNAS • November 2023
Gaussian Processes Hypergraphs Machine Learning Computational Science

This paper introduces Computational Hypergraph Discovery (CHD), a novel method for uncovering unknown functional relationships between variables within datasets, and represent them using a hypergraph.

Development and Assessment of an Artificial Intelligence-Based Tool for Ptosis Measurement in Adult Myasthenia Gravis Patients Using Selfie Video Clips Recorded on Smartphones
Development and Assessment of an Artificial Intelligence-Based Tool for Ptosis Measurement in Adult Myasthenia Gravis Patients Using Selfie Video Clips Recorded on Smartphones
Authors: Meelis Lootus, Lulu Beatson, Lucas Atwood, Theo Bourdais, Sandra Steyaert, Chethan Sarabu, Zeenia Framroze, Harriet Dickinson, Jean-Christophe Steels, Emily Lewis, Nirav R Shah and Francesca Rinaldo
Published in: Digital Biomarkers • May 2023
Computer Vision Medical AI Myasthenia Gravis Mobile Health

My first paper! This paper describes the work we did at Doc.ai for ShareCare on Myasthenia gravis (MG) with UCB. We developed a Deep Learning model based on ResNet50 to predict a key symptom of MG via selfie. This would allow clinical trials to accept more patients as part of a study in order to scale it, as well as follow almost in real time the evolution of a patient's symptoms using an app on their phone.